徐媛曼 教授

Hsu, Yuan-Man

E-mail：yuanmh@thu.edu.tw

徐媛曼(第十一家族)Hsu, Yuan-Man
職稱
Title		特聘教授
Distinguished Professor
學生訪談時間
Students time		星期三 9:00~12:00
Wed. 9:00~12:00
聯絡方式
Contact		Tel: 886-04-23590121轉37114
Fax: 886-04-23590385 
E-mail: yuanmh@thu.edu.tw
學經歷
Background		美國康乃爾大學獸醫學院群體醫學及診斷學研究所博士
Ph.D. in Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
國立台灣大學獸醫學系學士
Bachelor in Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan
研究方向
Research		微生物學、分子生物學、細菌致病機轉、中草藥結合益生菌之動物保健產品開發
Microbiology, Molecular Biology, Bacterial Pathogenesis, Development of animal health supplements combined with herbal medicine and probiotics
授課名稱
Courses		研究所 Graduate Program
消化道微生物特論(3-0)
Advanced Gastrointestinal microflora (3-0)
生物醫學研究方法(2-0)
Research Methodology of Molecular Medicine(2-0)
微生物遺傳學特論(3-0)
Advanced Microbial Genetics (3-0)

細菌致病機轉、益生菌作用機制、中草藥結合益生菌之動物保健產品開發

Bacterial Pathogenesis, Probiotic Mechanisms of Action, and Development of animal health supplements combined with herbal medicine and probiotics

  1. Tsai, S. C.; Lu, C. C.; Bau, D. T.; Chiu, Y. J.; Yen, Y. T.; Hsu, Y. M.; Fu, C. W.; Kuo, S. C.; Lo, Y. S.; Chiu, H. Y.; Juan, Y. N.; Tsai, F. J.; Yang, J. S., Approaches towards fighting the COVID-19 pandemic (Review). International Journal of Molecular Medicine 2021, 47 (1), 3-22. (SCI期刊)
  2. Do, A. D.; Chang, C. C.; Su, C. H.; Hsu, Y. M.*, Lactobacillus rhamnosus JB3 inhibits Helicobacter pylori infection through multiple molecular actions. Helicobacter 2021, 26 (3). (SCI期刊)
  3. Chang, P. Y.; Tsai, F. J.; Bau, D. T.; Hsu, Y. M.; Yang, J. S.; Tu, M. G.; Chiang, S. L., Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells. Journal of the Formosan Medical Association 2021, 120 (1), 515-523. (SCI期刊)
  4. Yang, J. S.; Chiang, J. H.; Tsai, S. C.; Hsu, Y. M.; Bau, D. T.; Lee, K. H.; Tsai, F. J., In Silico De Novo Curcuminoid Derivatives From the Compound Library of Natural Products Research Laboratories Inhibit COVID-19 3CL(pro) Activity. Natural Product Communications 2020, 15 (9). (SCI期刊)
  5. Tsai, C. B.; Hsia, N. Y.; Wang, Z. H.; Yang, J. S.; Hsu, Y. M.; Wang, Y. C.; Chang, W. S.; Bau, D. T.; Yin, M. C.; Tsai, C. W., The Contribution of MMP-9 Genotypes to Pterygium in Taiwan. Anticancer Research 2020, 40 (8), 4523-4527. (SCI期刊)
  6. Liu, S. P.; Shibu, M. A.; Tsai, F. J.; Hsu, Y. M.; Tsai, C. H.; Chung, J. G.; Yang, J. S.; Tang, C. H.; Wang, S. L.; Li, Q. W.; Huang, C. Y., Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1 alpha induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis. Nutrition & Metabolism 2020, 17 (1). (SCI期刊)
  7. Lin, C. C.; Huang, W. C.; Su, C. H.; Lin, W. D.; Wu, W. T.; Yu, B.; Hsu, Y. M.*, Effects of Multi-Strain Probiotics on Immune Responses and Metabolic Balance in Helicobacter pylori-Infected Mice. Nutrients 2020, 12 (8). (SCI期刊)
  8. Huang, T. Y.; Peng, S. F.; Huang, Y. P.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Huang, W. W.; Chung, J. G., Combinational treatment of all-trans retinoic acid (ATRA) and bisdemethoxycurcumin (BDMC)-induced apoptosis in liver cancer Hep3B cells. Journal of Food Biochemistry 2020, 44 (2). (SCI期刊)
  9. Chiang, J. H.; Tsai, F. J.; Hsu, Y. M.; Yin, M. C.; Chiu, H. Y.; Yang, J. S., Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells. Oncology Reports 2020, 44 (4), 1415-1424. (SCI期刊)
  10. Wu, K. M.; Hsu, Y. M.; Ying, M. C.; Tsai, F. J.; Tsai, C. H.; Chung, J. G.; Yang, J. S.; Tang, C. H.; Cheng, L. Y.; Su, P. H.; Viswanadha, V. P.; Kuo, W. W.; Huang, C. Y., High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression. Nutrition & Metabolism 2019, 16. (SCI期刊)
  11. Lu, C. C.; Chiang, J. H.; Tsai, F. J.; Hsu, Y. M.; Juan, Y. N.; Yang, J. S.; Chiu, H. Y., Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. International Journal of Oncology 2019, 54 (4), 1271-1281. (SCI期刊)
  12. Liu, S. C.; Tsai, C. H.; Wu, T. Y.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Wu, Y. C.; Tang, C. H., Soya-cerebroside reduces IL-1 beta-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis. Food and Agricultural Immunology 2019, 30 (1), 620-632. (SCI期刊)
  13. Lin, K. H.; Li, C. Y.; Hsu, Y. M.; Tsai, C. H.; Tsai, F. J.; Tang, C. H.; Yang, J. S.; Wang, Z. H.; Yin, M. C., Oridonin, A natural diterpenoid, protected NGF-differentiated PC12 cells against MPP+ – and kainic acid-induced injury. Food and Chemical Toxicology 2019, 133. (SCI期刊)
  14. Lin, C. C.; Chen, K. B.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Peng, S. F.; Chung, J. G., Casticin inhibits human prostate cancer DU 145 cell migration and invasion via Ras/Akt/NF-kappa B signaling pathways. Journal of Food Biochemistry 2019, 43 (7). (SCI期刊)
  15. Lee, H. P.; Wang, S. W.; Wu, Y. C.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Li, T. M.; Tang, C. H., Glucocerebroside reduces endothelial progenitor cell-induced angiogenesis. Food and Agricultural Immunology 2019, 30 (1), 1033-1045. (SCI期刊)
  16. Lee, H. P.; Chen, P. C.; Wang, S. W.; Fong, Y. C.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Li, T. M.; Tang, C. H., Plumbagin suppresses endothelial progenitor cell-related angiogenesis in vitro and in vivo. Journal of Functional Foods 2019, 52, 537-544. (SCI期刊)
  17. Hsu, M. J.; Peng, S. F.; Chueh, F. S.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Huang, W. W.; Chung, J. G., Lupeol suppresses migration and invasion via p38/MAPK and PI3K/Akt signaling pathways in human osteosarcoma U-2 OS cells. Bioscience Biotechnology and Biochemistry 2019, 83 (9), 1729-1739. (SCI期刊)
  18. Chen, C. C.; Chueh, F. S.; Peng, S. F.; Huang, W. W.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Huang, Y. P.; Chung, J. G., Cantharidin decreased viable cell number in human osteosarcoma U-2 OS cells through G(2)/M phase arrest and induction of cell apoptosis. Bioscience Biotechnology and Biochemistry 2019, 83 (10), 1912-1923. (SCI期刊)
  19. Chang, C. H.; Fu, J. H.; Su, C. H.; Yin, M. C.; Hsu, Y. M.*, Four spices prevent mice from contracting Salmonella enterica serovar Typhimurium. Experimental and Therapeutic Medicine 2019, 18 (4), 2956-2964. (SCI期刊)
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