{"id":7239,"date":"2021-10-01T18:15:52","date_gmt":"2021-10-01T10:15:52","guid":{"rendered":"https:\/\/animal.pathd.cc\/en\/?p=7239"},"modified":"2025-12-08T11:53:40","modified_gmt":"2025-12-08T03:53:40","slug":"hsu-yuan-man","status":"publish","type":"post","link":"https:\/\/animal.thu.edu.tw\/en\/faculty\/faculty1\/hsu-yuan-man\/","title":{"rendered":"Hsu, Yuan-Man"},"content":{"rendered":"\n<div class=\"wp-block-qubely-row qubely-section qubely-block-18f444\"><div class=\"qubely-row-overlay\"><\/div><div class=\"qubely-container\"><div class=\"qubely-row \">\n<div class=\"wp-block-qubely-column qubely-column qubely-column-front qubely-block-388152\"><div class=\"qubely-column-inner\">\n<div class=\"wp-block-qubely-image qubely-block-d7cba6 phd_remove_padding\"><div class=\"qubely-block-image  qubely-image-layout-simple\"><div class=\"qubely-image-media qubely-vertical-alignment-center qubely-horizontal-alignment-center\"><figure><div class=\"qubely-image-container\"><img decoding=\"async\" class=\"qubely-image-image\" src=\"https:\/\/animal.thu.edu.tw\/en\/wp-content\/uploads\/5-\u5f90\u5a9b\u66fc-\u6559\u6388-2.jpg\" alt=\"\"\/><\/div><\/figure><\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-qubely-column qubely-column qubely-column-front qubely-block-a53fc5\"><div class=\"qubely-column-inner\">\n<div class=\"wp-block-qubely-heading qubely-block-4a0197\"><div class=\"qubely-block-heading  \"><div class=\"qubely-heading-container\"><h2 class=\"qubely-heading-selector\"><meta charset=\"utf-8\"><\/meta>\u5f90\u5a9b\u66fc \u7279\u8058\u6559\u6388\u66a8\u7cfb\u4e3b\u4efb<\/h2><\/div><h3 class=\"qubely-sub-heading-selector\"><meta charset=\"utf-8\"><strong>Hsu, Yuan-Man<\/strong><\/h3><\/div><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><meta charset=\"utf-8\">E-mail\uff1a<a rel=\"noreferrer noopener\" href=\"mailto:yuanmh@thu.edu.tw\" target=\"_blank\"><\/a><a href=\"mailto:yuanmh@thu.edu.tw\">yuanmh@thu.edu.tw<\/a><\/p>\n<\/div><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-qubely-row qubely-section qubely-block-f64536\"><div class=\"qubely-row-overlay\"><\/div><div class=\"qubely-container\"><div class=\"qubely-row \">\n<div class=\"wp-block-qubely-column qubely-column qubely-column-front qubely-block-076ae5\"><div class=\"qubely-column-inner\">\n<div class=\"wp-block-uagb-tabs uagb-block-a0be3d4a uagb-tabs__wrap uagb-tabs__hstyle5-desktop uagb-tabs__vstyle6-tablet uagb-tabs__vstyle6-mobile\" data-tab-active=\"0\"><ul class=\"uagb-tabs__panel uagb-tabs__align-left\" role=\"tablist\"><li class=\"uagb-tab uagb-tabs__active\" role=\"none\"><a href=\"#uagb-tabs__tab0\" class=\"uagb-tabs-list uagb-tabs__icon-position-left\" data-tab=\"0\" role=\"tab\"><div>Profile<\/div><\/a><\/li><li class=\"uagb-tab \" role=\"none\"><a href=\"#uagb-tabs__tab1\" class=\"uagb-tabs-list uagb-tabs__icon-position-left\" data-tab=\"1\" role=\"tab\"><div>Research<\/div><\/a><\/li><li class=\"uagb-tab \" role=\"none\"><a href=\"#uagb-tabs__tab2\" class=\"uagb-tabs-list uagb-tabs__icon-position-left\" data-tab=\"2\" role=\"tab\"><div>Publication<\/div><\/a><\/li><\/ul><div class=\"uagb-tabs__body-wrap\">\n<div class=\"wp-block-uagb-tabs-child uagb-tabs__body-container uagb-inner-tab-0\" aria-labelledby=\"uagb-tabs__tab0\">\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>\u5f90\u5a9b\u66fc(\u7b2c\u5341\u4e00\u5bb6\u65cf)<\/strong><\/td><td>Hsu, Yuan-Man<\/td><\/tr><tr><td><strong>\u8077\u7a31<br>Title<\/strong><\/td><td>\u7279\u8058\u6559\u6388<br>Distinguished Professor<\/td><\/tr><tr><td><strong>\u5b78\u751f\u8a2a\u8ac7\u6642\u9593<br>Students time<\/strong><\/td><td>\u661f\u671f\u4e09&nbsp;9:00~12:00<br>Wed. 9:00~12:00<\/td><\/tr><tr><td><strong>\u806f\u7d61\u65b9\u5f0f<br>Contact<\/strong><\/td><td>Tel: 886-04-23590121\u8f4937114<br>Fax: 886-04-23590385&nbsp;<br>E-mail:  <a href=\"mailto:yuanmh@thu.edu.tw\">yuanmh@thu.edu.tw<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>\u5b78\u7d93\u6b77<br>Background<\/strong><\/td><td>\u7f8e\u570b\u5eb7\u4e43\u723e\u5927\u5b78\u7378\u91ab\u5b78\u9662\u7fa4\u9ad4\u91ab\u5b78\u53ca\u8a3a\u65b7\u5b78\u7814\u7a76\u6240\u535a\u58eb<br>Ph.D. in Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA<br>\u570b\u7acb\u53f0\u7063\u5927\u5b78\u7378\u91ab\u5b78\u7cfb\u5b78\u58eb<br>Bachelor in&nbsp;Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan<\/td><\/tr><tr><td><strong>\u7814\u7a76\u65b9\u5411<br>Research<\/strong><\/td><td>\u5fae\u751f\u7269\u5b78\u3001\u5206\u5b50\u751f\u7269\u5b78\u3001\u7d30\u83cc\u81f4\u75c5\u6a5f\u8f49\u3001\u4e2d\u8349\u85e5\u7d50\u5408\u76ca\u751f\u83cc\u4e4b\u52d5\u7269\u4fdd\u5065\u7522\u54c1\u958b\u767c<br>Microbiology, Molecular Biology, Bacterial Pathogenesis, Development of animal health supplements combined with herbal medicine and probiotics<\/td><\/tr><tr><td><strong>\u6388\u8ab2\u540d\u7a31<br>Courses<\/strong><\/td><td><strong><strong>\u7814\u7a76\u6240&nbsp;Graduate Program<\/strong><br><\/strong>\u6d88\u5316\u9053\u5fae\u751f\u7269\u7279\u8ad6(3-0)<br>Advanced Gastrointestinal microflora (3-0)<br>\u751f\u7269\u91ab\u5b78\u7814\u7a76\u65b9\u6cd5(2-0)<br>Research Methodology of Molecular Medicine(2-0)<br>\u5fae\u751f\u7269\u907a\u50b3\u5b78\u7279\u8ad6(3-0)<br>Advanced Microbial Genetics (3-0)<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-tabs-child uagb-tabs__body-container uagb-inner-tab-1\" aria-labelledby=\"uagb-tabs__tab1\">\n<p>\u7d30\u83cc\u81f4\u75c5\u6a5f\u8f49\u3001\u76ca\u751f\u83cc\u4f5c\u7528\u6a5f\u5236\u3001\u4e2d\u8349\u85e5\u7d50\u5408\u76ca\u751f\u83cc\u4e4b\u52d5\u7269\u4fdd\u5065\u7522\u54c1\u958b\u767c<\/p>\n\n\n\n<p>Bacterial Pathogenesis, Probiotic Mechanisms of Action, and Development of animal health supplements combined with herbal medicine and probiotics<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-tabs-child uagb-tabs__body-container uagb-inner-tab-2\" aria-labelledby=\"uagb-tabs__tab2\">\n<ol class=\"wp-block-list\">\n<li>Tsai, S. C.; Lu, C. C.; Bau, D. T.; Chiu, Y. J.; Yen, Y. T.; Hsu, Y. M.; Fu, C. W.; Kuo, S. C.; Lo, Y. S.; Chiu, H. Y.; Juan, Y. N.; Tsai, F. J.; Yang, J. S., Approaches towards fighting the COVID-19 pandemic (Review). International Journal of Molecular Medicine 2021, 47 (1), 3-22. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Do, A. D.; Chang, C. C.; Su, C. H.; Hsu, Y. M.*, Lactobacillus rhamnosus JB3 inhibits Helicobacter pylori infection through multiple molecular actions. Helicobacter 2021, 26 (3). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Chang, P. Y.; Tsai, F. J.; Bau, D. T.; Hsu, Y. M.; Yang, J. S.; Tu, M. G.; Chiang, S. L., Potential effects of allyl isothiocyanate on inhibiting cellular proliferation and inducing apoptotic pathway in human cisplatin-resistant oral cancer cells. Journal of the Formosan Medical Association 2021, 120 (1), 515-523. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Yang, J. S.; Chiang, J. H.; Tsai, S. C.; Hsu, Y. M.; Bau, D. T.; Lee, K. H.; Tsai, F. J., In Silico De Novo Curcuminoid Derivatives From the Compound Library of Natural Products Research Laboratories Inhibit COVID-19 3CL(pro) Activity. Natural Product Communications 2020, 15 (9). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Tsai, C. B.; Hsia, N. Y.; Wang, Z. H.; Yang, J. S.; Hsu, Y. M.; Wang, Y. C.; Chang, W. S.; Bau, D. T.; Yin, M. C.; Tsai, C. W., The Contribution of MMP-9 Genotypes to Pterygium in Taiwan. Anticancer Research 2020, 40 (8), 4523-4527. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Liu, S. P.; Shibu, M. A.; Tsai, F. J.; Hsu, Y. M.; Tsai, C. H.; Chung, J. G.; Yang, J. S.; Tang, C. H.; Wang, S. L.; Li, Q. W.; Huang, C. Y., Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1 alpha induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis. Nutrition &amp; Metabolism 2020, 17 (1). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lin, C. C.; Huang, W. C.; Su, C. H.; Lin, W. D.; Wu, W. T.; Yu, B.; Hsu, Y. M.*, Effects of Multi-Strain Probiotics on Immune Responses and Metabolic Balance in Helicobacter pylori-Infected Mice. Nutrients 2020, 12 (8). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Huang, T. Y.; Peng, S. F.; Huang, Y. P.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Huang, W. W.; Chung, J. G., Combinational treatment of all-trans retinoic acid (ATRA) and bisdemethoxycurcumin (BDMC)-induced apoptosis in liver cancer Hep3B cells. Journal of Food Biochemistry 2020, 44 (2). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Chiang, J. H.; Tsai, F. J.; Hsu, Y. M.; Yin, M. C.; Chiu, H. Y.; Yang, J. S., Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells. Oncology Reports 2020, 44 (4), 1415-1424. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Wu, K. M.; Hsu, Y. M.; Ying, M. C.; Tsai, F. J.; Tsai, C. H.; Chung, J. G.; Yang, J. S.; Tang, C. H.; Cheng, L. Y.; Su, P. H.; Viswanadha, V. P.; Kuo, W. W.; Huang, C. Y., High-density lipoprotein ameliorates palmitic acid-induced lipotoxicity and oxidative dysfunction in H9c2 cardiomyoblast cells via ROS suppression. Nutrition &amp; Metabolism 2019, 16. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lu, C. C.; Chiang, J. H.; Tsai, F. J.; Hsu, Y. M.; Juan, Y. N.; Yang, J. S.; Chiu, H. Y., Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR\/AKT signaling. International Journal of Oncology 2019, 54 (4), 1271-1281. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Liu, S. C.; Tsai, C. H.; Wu, T. Y.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Wu, Y. C.; Tang, C. H., Soya-cerebroside reduces IL-1 beta-induced MMP-1 production in chondrocytes and inhibits cartilage degradation: implications for the treatment of osteoarthritis. Food and Agricultural Immunology 2019, 30 (1), 620-632. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lin, K. H.; Li, C. Y.; Hsu, Y. M.; Tsai, C. H.; Tsai, F. J.; Tang, C. H.; Yang, J. S.; Wang, Z. H.; Yin, M. C., Oridonin, A natural diterpenoid, protected NGF-differentiated PC12 cells against MPP+ &#8211; and kainic acid-induced injury. Food and Chemical Toxicology 2019, 133. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lin, C. C.; Chen, K. B.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Peng, S. F.; Chung, J. G., Casticin inhibits human prostate cancer DU 145 cell migration and invasion via Ras\/Akt\/NF-kappa B signaling pathways. Journal of Food Biochemistry 2019, 43 (7). (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lee, H. P.; Wang, S. W.; Wu, Y. C.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Li, T. M.; Tang, C. H., Glucocerebroside reduces endothelial progenitor cell-induced angiogenesis. Food and Agricultural Immunology 2019, 30 (1), 1033-1045. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Lee, H. P.; Chen, P. C.; Wang, S. W.; Fong, Y. C.; Tsai, C. H.; Tsai, F. J.; Chung, J. G.; Huang, C. Y.; Yang, J. S.; Hsu, Y. M.; Li, T. M.; Tang, C. H., Plumbagin suppresses endothelial progenitor cell-related angiogenesis in vitro and in vivo. Journal of Functional Foods 2019, 52, 537-544. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Hsu, M. J.; Peng, S. F.; Chueh, F. S.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Huang, W. W.; Chung, J. G., Lupeol suppresses migration and invasion via p38\/MAPK and PI3K\/Akt signaling pathways in human osteosarcoma U-2 OS cells. Bioscience Biotechnology and Biochemistry 2019, 83 (9), 1729-1739. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Chen, C. C.; Chueh, F. S.; Peng, S. F.; Huang, W. W.; Tsai, C. H.; Tsai, F. J.; Huang, C. Y.; Tang, C. H.; Yang, J. S.; Hsu, Y. M.; Yin, M. C.; Huang, Y. P.; Chung, J. G., Cantharidin decreased viable cell number in human osteosarcoma U-2 OS cells through G(2)\/M phase arrest and induction of cell apoptosis. Bioscience Biotechnology and Biochemistry 2019, 83 (10), 1912-1923. (SCI\u671f\u520a)<\/li>\n\n\n\n<li>Chang, C. H.; Fu, J. H.; Su, C. H.; Yin, M. C.; Hsu, Y. M.*, Four spices prevent mice from contracting Salmonella enterica serovar Typhimurium. Experimental and Therapeutic Medicine 2019, 18 (4), 2956-2964. (SCI\u671f\u520a)<\/li>\n<\/ol>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Professor<\/p>\n","protected":false},"author":2,"featured_media":7241,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"qubely_global_settings":"","qubely_interactions":"","_uag_custom_page_level_css":"","site-sidebar-layout":"left-sidebar","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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